Saffron

NCBI Taxonomy ID: 82528
Common Names: Saffron, Saffron Crocu, Saffron Crocus
Scientific Name: Crocus Sativus
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Diseases associated with Saffron

Diseases Association Details
Depressive Disorder 22, 0
Associations of Saffron with Depressive Disorder
PMID Disease Title Journal Year
27723543 Depressive Disorder Efficacy of curcumin, and a saffron/c... Journal of affective disorders 2017
27595298 Depressive Disorder Comparison of Saffron versus Fluoxeti... Pharmacopsychiatry 2017
27701683 Depressive Disorder Crocus sativus L. versus Citalopram i... Pharmacopsychiatry 2017
27101556 Depressive Disorder A double-blind, randomized and placeb... Journal of complementary & integrativ... 2016
26681074 Depressive Disorder Can bioactive compounds of Crocus sat... Physiological research 2015
26276913 Depressive Disorder Natural products of relevance in the ... Psychiatria polska 2015
26165367 Depressive Disorder A systematic review of randomized con... Journal of integrative medicine 2015
25714974 Depressive Disorder Neuropharmacological Aspects of Crocu... CNS & neurological disorders drug tar... 2015
26468457 Depressive Disorder The effects of Crocus sativus (saffro... Avicenna journal of phytomedicine 2015
26272123 Depressive Disorder Saffron: a natural product with poten... The Journal of pharmacy and pharmacology 2015
26124935 Depressive Disorder Inhibitory effect of corcin on aggreg... Iranian journal of basic medical scie... 2015
25384672 Depressive Disorder Saffron (Crocus sativus) for depressi... Human psychopharmacology 2014
24289892 Depressive Disorder A randomized, double-blind, clinical ... Journal of affective disorders 2014
24299602 Depressive Disorder Saffron (Crocus sativus L.) and major... Journal of integrative medicine 2013
22414105 Depressive Disorder Nature against depression. Current medicinal chemistry 2012
21352900 Depressive Disorder Saffron extract and trans-crocetin in... Neuroscience 2011
18496783 Depressive Disorder Quality and functionality of saffron:... Planta medica 2008
17562566 Depressive Disorder Herbal medicines in the treatment of ... Phytotherapy research : PTR 2007
16979327 Depressive Disorder Crocus sativus L. (petal) in the trea... Phytomedicine : international journal... 2006
15707766 Depressive Disorder Hydro-alcoholic extract of Crocus sat... Journal of ethnopharmacology 2005
15852492 Depressive Disorder Crocus sativus L. in the treatment of... Phytotherapy research : PTR 2005
15341662 Depressive Disorder Comparison of Crocus sativus L. and i... BMC complementary and alternative med... 2004
No negative associations were obtained for Saffron with Depressive Disorder.


Linked Phytochemicals
PubChem ID Common Name Explore
24721245 Crocin I
Alzheimer Disease 14, 0
Associations of Saffron with Alzheimer Disease
PMID Disease Title Journal Year
27865556 Alzheimer Disease Trans-crocetin improves amyloid-β deg... Journal of the neurological sciences 2017
28471166 Alzheimer Disease Crocus sativus Extract Tightens the B... ACS chemical neuroscience 2017
27840509 Alzheimer Disease Medicinal Herbs in Iranian Traditiona... Iranian journal of medical sciences 2016
27516676 Alzheimer Disease Medicinal Herbs in Iranian Traditiona... Iranian journal of medical sciences 2016
25875654 Alzheimer Disease Efficacy and Safety of Saffron Supple... Critical reviews in food science and ... 2016
26272123 Alzheimer Disease Saffron: a natural product with poten... The Journal of pharmacy and pharmacology 2015
25714974 Alzheimer Disease Neuropharmacological Aspects of Crocu... CNS & neurological disorders drug tar... 2015
26468457 Alzheimer Disease The effects of Crocus sativus (saffro... Avicenna journal of phytomedicine 2015
24848002 Alzheimer Disease Clinical Applications of Saffron (Cro... Drug research 2015
25163440 Alzheimer Disease Comparing the efficacy and safety of ... Human psychopharmacology 2014
23938314 Alzheimer Disease Saffron pre-treatment offers neuropro... Journal of Parkinson's disease 2013
22655699 Alzheimer Disease Saffron as a source of novel acetylch... Journal of agricultural and food chem... 2012
20831681 Alzheimer Disease Saffron in the treatment of patients ... Journal of clinical pharmacy and ther... 2010
19838862 Alzheimer Disease A 22-week, multicenter, randomized, d... Psychopharmacology 2010
No negative associations were obtained for Saffron with Alzheimer Disease.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Alzheimer Disease association.
Neoplasms 10, 0
Associations of Saffron with Neoplasms
PMID Disease Title Journal Year
28496478 Neoplasms Study of Crocin & Radiotherapy-in... Iranian journal of pharmaceutical res... 2017
27529277 Neoplasms Spices for Prevention and Treatment o... Nutrients 2016
25395243 Neoplasms Chemo-immunotherapy using saffron and... Archives of virology 2015
24834315 Neoplasms The Synergic Effects of Crocus Sativu... Avicenna journal of medical biotechno... 2014
25124576 Neoplasms Distinct pro-apoptotic properties of ... Asian Pacific journal of cancer preve... 2014
23494763 Neoplasms Assessment of cytotoxic properties of... Phytotherapy research : PTR 2013
21466430 Neoplasms Crocetin: an agent derived from saffr... Current pharmaceutical biotechnology 2012
20104983 Neoplasms Crocin from Kashmiri saffron (Crocus ... Asian Pacific journal of cancer preve... 2009
18790714 Neoplasms Study of cytotoxic and apoptogenic pr... Food and chemical toxicology : an int... 2008
18825622 Neoplasms Cytotoxic effect of saffron stigma aq... Urology journal 2008
No negative associations were obtained for Saffron with Neoplasms.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Neoplasms association.
Diabetes Mellitus 9, 0
Associations of Saffron with Diabetes Mellitus
PMID Disease Title Journal Year
27861946 Diabetes Mellitus Saffron: a promising natural medicine... Journal of the science of food and ag... 2017
28460761 Diabetes Mellitus Immunomodulatory and antioxidant effe... Indian heart journal 2017
27122001 Diabetes Mellitus Saffron with resistance exercise impr... Scientific reports 2016
26272123 Diabetes Mellitus Saffron: a natural product with poten... The Journal of pharmacy and pharmacology 2015
25948674 Diabetes Mellitus Effects of a Topical Saffron (Crocus ... Journal of evidence-based complementa... 2015
26600752 Diabetes Mellitus Anti-atherogenic potential of jujube,... EXCLI journal 2015
26639503 Diabetes Mellitus Hypoglycemic effects of three Iranian... Pakistan journal of pharmaceutical sc... 2015
25114929 Diabetes Mellitus Ameliorative effect of saffron aqueou... BioMed research international 2014
22980812 Diabetes Mellitus Saffron (Crocus sativus L.) increases... Food chemistry 2012
No negative associations were obtained for Saffron with Diabetes Mellitus.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Diabetes Mellitus association.
Ischemia 7, 0
Associations of Saffron with Ischemia
PMID Disease Title Journal Year
27109157 Ischemia Crocin-Elicited Autophagy Rescues Myo... The American journal of Chinese medicine 2016
25875654 Ischemia Efficacy and Safety of Saffron Supple... Critical reviews in food science and ... 2016
27507116 Ischemia Saffron (Crocus sativus) pretreatment... Journal of physiology and biochemistry 2016
25854766 Ischemia Cardioprotective effect of saffron ex... Zeitschrift fur Naturforschung. C, Jo... 2014
22070681 Ischemia Polyphenols and neuroprotection again... Mini reviews in medicinal chemistry 2011
20119744 Ischemia The effect of saffron consumption on ... Cardiovascular toxicology 2010
18955256 Ischemia Crocus sativus L. (Saffron) extract a... Evidence-based complementary and alte... 2009
No negative associations were obtained for Saffron with Ischemia.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Ischemia association.
Breast Neoplasms 7, 0
Associations of Saffron with Breast Neoplasms
PMID Disease Title Journal Year
27648633 Breast Neoplasms A combination of complexation and sel... Drug development and industrial pharmacy 2017
27039797 Breast Neoplasms Molecular Mechanism of Crocin Induced... Asian Pacific journal of cancer preve... 2016
26394119 Breast Neoplasms Effect of Crocin on Cell Cycle Regula... DNA and cell biology 2015
24834315 Breast Neoplasms The Synergic Effects of Crocus Sativu... Avicenna journal of medical biotechno... 2014
23347444 Breast Neoplasms Crocin triggers the apoptosis through... DNA and cell biology 2013
20803418 Breast Neoplasms Crocetin inhibits invasiveness of MDA... Planta medica 2011
19457443 Breast Neoplasms Role of caspases and Bax protein in s... Food and chemical toxicology : an int... 2009
No negative associations were obtained for Saffron with Breast Neoplasms.


Linked Phytochemicals
PubChem ID Common Name Explore
5280863 Kaempferol
Neuralgia 5, 0
Associations of Saffron with Neuralgia
PMID Disease Title Journal Year
28496474 Neuralgia Enhancement of Antinociceptive Effect... Iranian journal of pharmaceutical res... 2017
27610166 Neuralgia Effects of Saffron (Crocus sativus L.... Iranian journal of pharmaceutical res... 2016
25493695 Neuralgia Attenuation of oxidative stress, infl... Anais da Academia Brasileira de Ciencias 2014
25590719 Neuralgia Attenuation of oxidative stress, infl... Anais da Academia Brasileira de Ciencias 2014
22484092 Neuralgia Evaluation of aqueous and ethanolic e... Fitoterapia 2012
No negative associations were obtained for Saffron with Neuralgia.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Neuralgia association.
Cardiotoxicity 4, 0
Associations of Saffron with Cardiotoxicity
PMID Disease Title Journal Year
27297631 Cardiotoxicity Crocin treatment prevents doxorubicin... Life sciences 2016
25368905 Cardiotoxicity Evaluation of Protein Ubiquitylation ... Drug research 2015
25854766 Cardiotoxicity Cardioprotective effect of saffron ex... Zeitschrift fur Naturforschung. C, Jo... 2014
24003974 Cardiotoxicity Protective effect of saffron extract ... Pharmaceutical biology 2013
No negative associations were obtained for Saffron with Cardiotoxicity.


Linked Phytochemicals
PubChem ID Common Name Explore
637542 P-Coumaric Acid
24721245 Crocin I
Dementia 4, 0
Associations of Saffron with Dementia
PMID Disease Title Journal Year
27696408 Dementia Widespread brain transcriptome altera... Journal of neurochemistry 2016
26124935 Dementia Inhibitory effect of corcin on aggreg... Iranian journal of basic medical scie... 2015
22329652 Dementia Ethnobotanical treatment strategies a... Current Alzheimer research 2012
21639405 Dementia The role of phytochemicals in the tre... Drugs & aging 2011
No negative associations were obtained for Saffron with Dementia.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Dementia association.
Metabolic Diseases 4, 0
Associations of Saffron with Metabolic Diseases
PMID Disease Title Journal Year
27861946 Metabolic Diseases Saffron: a promising natural medicine... Journal of the science of food and ag... 2017
26468462 Metabolic Diseases Saffron supplements modulate serum pr... Avicenna journal of phytomedicine 2015
24501162 Metabolic Diseases Saffron in metabolic syndrome: its ef... Journal of complementary & integrativ... 2014
21592014 Metabolic Diseases Reduction of metabolic and behavioral... Pharmaceutical biology 2011
No negative associations were obtained for Saffron with Metabolic Diseases.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Saffron-Metabolic Diseases association.
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Phytochemicals in Saffron


PubChem ID Common Name Explore
5280899 Zeaxanthin
10095180 16290-07-6
130796 Picrocrocin
637542 P-Coumaric Acid
1174 Uracil
6436722 Phytofluene
5282102 Astragalin
61041 Safranal
5280863 Kaempferol
5282155 Sophoraflavonoloside
243 Benzoic Acid
60961 Adenosine
24721245 Crocin I
5281404 Harman
160179 Perlolyrine
5281666 Kaempferide
8468 Vanillic Acid
7456 Methyl 4-Hydroxybenzoate
72 3,4-Dihydroxybenzoic Acid
936 Nicotinamide
1135 Thymine
287064 Methyl 3,4-Dihydroxybenzoate
5491808 Isorhamnetin 3-O-Robinobioside
12575 3-Hydroxy-4-Methoxybenzoic Acid
5281232 Crocetin