Fenugreek

NCBI Taxonomy ID: 78534
Common Names: Fenugreek, Sicklefruit Fenugreek
Scientific Name: Trigonella Foenum-Graecum
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Diseases associated with Fenugreek

Diseases Association Details
Diabetes Mellitus 75, 0
Associations of Fenugreek with Diabetes Mellitus
PMID Disease Title Journal Year
28269780 Diabetes Mellitus Fenugreek Seed Powder Attenuated Alum... Journal of Alzheimer's disease : JAD 2017
28319671 Diabetes Mellitus Amelioration of oxidative stress by d... Applied physiology, nutrition, and me... 2017
28407664 Diabetes Mellitus Fenugreek, A Potent Hypoglycaemic Her... Experimental and clinical endocrinolo... 2017
28063302 Diabetes Mellitus Metabonomics study of the therapeutic... Journal of chromatography. B, Analyti... 2017
28566642 Diabetes Mellitus Modulatory Effect of an Isolated Trig... Journal of oleo science 2017
25922446 Diabetes Mellitus A Review on Ethnobotanical and Therap... Journal of evidence-based complementa... 2016
27151154 Diabetes Mellitus 4-Hydroxyisoleucine: A Potential New ... BioDrugs : clinical immunotherapeutic... 2016
27733237 Diabetes Mellitus A multicenter clinical study to deter... Food & nutrition research 2016
26778682 Diabetes Mellitus Alterations in Plasma Glucose and Car... Canadian journal of diabetes 2016
26699937 Diabetes Mellitus Evaluation of Trigonella foenum-graec... Food & nutrition research 2015
25339548 Diabetes Mellitus Hydroalcohol extract of Trigonella fo... Pharmaceutical biology 2015
25553366 Diabetes Mellitus Natural supplements for improving ins... Frontiers in bioscience (Elite edition) 2015
25938017 Diabetes Mellitus Effects of Fenugreek Seed Extract and... Osong public health and research pers... 2015
25530163 Diabetes Mellitus Diosgenin reorganises hyperglycaemia ... Journal of the science of food and ag... 2015
26400229 Diabetes Mellitus [Effectiveness of phytotherapy in sup... Ceska a Slovenska farmacie : casopis ... 2015
26436069 Diabetes Mellitus Role of Fenugreek in the prevention o... Journal of diabetes and metabolic dis... 2015
24615531 Diabetes Mellitus Fenugreek potent activity against nit... Cytotechnology 2015
25057273 Diabetes Mellitus Fenugreek Prevents the Development of... Evidence-based complementary and alte... 2014
25911840 Diabetes Mellitus Effects of fenugreek seeds on adipoge... Pakistan journal of biological scienc... 2014
24973886 Diabetes Mellitus Fenugreek extract diosgenin and pure ... Molecular biology reports 2014
24438170 Diabetes Mellitus Effect of fenugreek (Trigonella foenu... Nutrition journal 2014
24242137 Diabetes Mellitus Effects of Trigonella foenum-graecum ... Molecular and cellular biochemistry 2014
25331834 Diabetes Mellitus The use of complementary and alternat... Nutrition journal 2014
23606883 Diabetes Mellitus In Vitro Evaluations of Cytotoxicity ... Evidence-based complementary and alte... 2013
24289578 Diabetes Mellitus Fenugreek induced apoptosis in breast... Asian Pacific journal of cancer preve... 2013
23364205 Diabetes Mellitus Dietary spices as beneficial modulato... Food & function 2013
23497544 Diabetes Mellitus Evaluation of vegetable and fish oils... Journal of diabetes and metabolic dis... 2013
22397995 Diabetes Mellitus Non-insulin dependent anti-diabetic a... Phytomedicine : international journal... 2012
22680628 Diabetes Mellitus Trigonelline: a plant alkaloid with t... Current medicinal chemistry 2012
22237966 Diabetes Mellitus Fenugreek attenuation of diabetic nep... Journal of physiology and biochemistry 2012
23882364 Diabetes Mellitus Non-traditional therapies for diabete... Journal of community hospital interna... 2012
22329631 Diabetes Mellitus A review of the hypoglycemic effects ... Recent patents on food, nutrition & a... 2012
22957413 Diabetes Mellitus Effect of Trigonella foenum-graecum s... European review for medical and pharm... 2012
22508583 Diabetes Mellitus Beneficial effects of Trigonella foen... Cell biochemistry and function 2012
23781448 Diabetes Mellitus A validated RP-HPLC method for quanti... Pharmaceutical methods 2011
22471470 Diabetes Mellitus Fenugreek, a naturally occurring edib... Asian Pacific journal of cancer preve... 2011
21069315 Diabetes Mellitus A novel L-isoleucine metabolism in Ba... Applied microbiology and biotechnology 2011
21106928 Diabetes Mellitus Diosgenin, the main aglycon of fenugr... The Journal of nutrition 2011
21205429 Diabetes Mellitus Anti-metabolic syndrome and immunosti... The British journal of nutrition 2011
21840472 Diabetes Mellitus Trigonella foenum graecum seed extrac... Nutrition research (New York, N.Y.) 2011
21843614 Diabetes Mellitus Meta-analysis of the effect of herbal... Journal of ethnopharmacology 2011
21861724 Diabetes Mellitus The potential of fenugreek (Trigonell... Journal of medicinal food 2011
22142357 Diabetes Mellitus Inhibitory potential of omega-3 fatty... Lipids in health and disease 2011
20507258 Diabetes Mellitus Potential protective effect on key st... Archives of physiology and biochemistry 2010
20100065 Diabetes Mellitus Immunomodulatory, beta-cell, and neur... Immunopharmacology and immunotoxicology 2010
20540147 Diabetes Mellitus Diosgenin present in fenugreek improv... Molecular nutrition & food research 2010
18680121 Diabetes Mellitus The effect of fenugreek 4-hydroxyisol... Phytotherapy research : PTR 2009
19922253 Diabetes Mellitus Indigenous drugs in ischemic heart di... Journal of alternative and complement... 2009
19857068 Diabetes Mellitus Fenugreek bread: a treatment for diab... Journal of medicinal food 2009
19337956 Diabetes Mellitus 4-Hydroxyisoleucine: a plant-derived ... Current opinion in investigational dr... 2009
20716916 Diabetes Mellitus The plant extracts of Momordica chara... Oxidative medicine and cellular longe... 2009
19839001 Diabetes Mellitus Effect of fenugreek seeds on blood gl... International journal for vitamin and... 2009
21785655 Diabetes Mellitus Possible fenugreek induced haemolysis... BMJ case reports 2009
18296352 Diabetes Mellitus Traditional Indian spices and their h... Asia Pacific journal of clinical nutr... 2008
17392143 Diabetes Mellitus Effect of Trigonella foenum-graecum (... Asia Pacific journal of clinical nutr... 2007
17313713 Diabetes Mellitus Soluble dietary fibre fraction of Tri... The British journal of nutrition 2007
16328970 Diabetes Mellitus Biochemical study of the anti-diabeti... Molecular and cellular biochemistry 2006
16718375 Diabetes Mellitus Long-term effect of Trigonella foenum... Molecular and cellular biochemistry 2006
16180085 Diabetes Mellitus Restoration of ultrastructural and bi... Molecular and cellular biochemistry 2005
16021836 Diabetes Mellitus Modulatory effect of fenugreek seed m... Plant foods for human nutrition (Dord... 2005
16176151 Diabetes Mellitus Supplementation of fenugreek leaves r... Journal of medicinal food 2005
15738612 Diabetes Mellitus Effect of fenugreek, onion and garlic... Indian journal of medical sciences 2005
15350674 Diabetes Mellitus Genotoxicity testing of a fenugreek e... Food and chemical toxicology : an int... 2004
15298963 Diabetes Mellitus Diosgenin, a steroid saponin of Trigo... Cancer epidemiology, biomarkers & pre... 2004
15284693 Diabetes Mellitus Effect of fenugreek seeds on the fast... Mymensingh medical journal : MMJ 2004
15286407 Diabetes Mellitus Effects of sodium-orthovanadate and T... Journal of biosciences 2004
14669264 Diabetes Mellitus Supplementation of fenugreek leaves t... Phytotherapy research : PTR 2003
12902054 Diabetes Mellitus Effect of soluble dietary fibre fract... Journal of ethnopharmacology 2003
12190123 Diabetes Mellitus Alterations in antioxidant enzymes an... Molecular and cellular biochemistry 2002
11868855 Diabetes Mellitus Effect of Trigonella foenum-graecum (... The Journal of the Association of Phy... 2001
11103307 Diabetes Mellitus Development of food products based on... International journal of food science... 2000
10997530 Diabetes Mellitus Alternative therapies: Part I. Depres... American family physician 2000
9324004 Diabetes Mellitus Phytotherapy of hypertension and diab... Journal of ethnopharmacology 1997
2194788 Diabetes Mellitus Effect of fenugreek seeds on blood gl... European journal of clinical nutrition 1990
3032826 Diabetes Mellitus New sources of dietary fibre. International journal of obesity 1987
No negative associations were obtained for Fenugreek with Diabetes Mellitus.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Diabetes Mellitus association.
Inflammation 10, 0
Associations of Fenugreek with Inflammation
PMID Disease Title Journal Year
28269780 Inflammation Fenugreek Seed Powder Attenuated Alum... Journal of Alzheimer's disease : JAD 2017
25996647 Inflammation Fenugreek seed extract attenuates cis... Andrologia 2016
24289578 Inflammation Fenugreek induced apoptosis in breast... Asian Pacific journal of cancer preve... 2013
22395729 Inflammation Effect of ethanol extract of Trigonel... Inflammation 2012
21756271 Inflammation Dietary fenugreek and onion attenuate... International journal of experimental... 2011
22471470 Inflammation Fenugreek, a naturally occurring edib... Asian Pacific journal of cancer preve... 2011
20540147 Inflammation Diosgenin present in fenugreek improv... Molecular nutrition & food research 2010
17324542 Inflammation Effects of aqueous extracts of medici... Journal of ethnopharmacology 2007
16331273 Inflammation Diosgenin inhibits osteoclastogenesis... Oncogene 2006
15298963 Inflammation Diosgenin, a steroid saponin of Trigo... Cancer epidemiology, biomarkers & pre... 2004
No negative associations were obtained for Fenugreek with Inflammation.


Linked Phytochemicals
PubChem ID Common Name Explore
5280445 Luteolin
5280343 Quercetin
689043 Caffeic Acid
5281654 Isorhamnetin
Obesity 7, 0
Associations of Fenugreek with Obesity
PMID Disease Title Journal Year
27879673 Obesity 4-Hydroxyisoleucine from Fenugreek (T... Molecules (Basel, Switzerland) 2016
25276421 Obesity Trigonella foenum-graecum seeds lower... Journal of nutrition and metabolism 2014
21205429 Obesity Anti-metabolic syndrome and immunosti... The British journal of nutrition 2011
21069315 Obesity A novel L-isoleucine metabolism in Ba... Applied microbiology and biotechnology 2011
19353539 Obesity Effect of fenugreek fiber on satiety,... Phytotherapy research : PTR 2009
16477270 Obesity Alleviation of hepatic steatosis acco... International journal of obesity (2005) 2006
15973051 Obesity Effects of fenugreek seed extract in ... Bioscience, biotechnology, and bioche... 2005
No negative associations were obtained for Fenugreek with Obesity.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Obesity association.
Chemical and Drug Induced Liver Injury 6, 0
Associations of Fenugreek with Chemical and Drug Induced Liver Injury
PMID Disease Title Journal Year
26612737 Chemical and Drug Induced Liver Injury Ethanolic extract of Trigonella Foenu... Cellular and molecular biology (Noisy... 2015
24600306 Chemical and Drug Induced Liver Injury Protective effect of Trigonella foenu... Saudi journal of biological sciences 2014
23363543 Chemical and Drug Induced Liver Injury Fenugreek seeds, a hepatoprotector fo... BMC veterinary research 2013
22082829 Chemical and Drug Induced Liver Injury Effect of fenugreek seed extract on a... Toxicology and industrial health 2012
17484288 Chemical and Drug Induced Liver Injury Fenugreek (Trigonella foenum graecum)... Die Pharmazie 2007
16574673 Chemical and Drug Induced Liver Injury Fenugreek (Trigonella foenum graecum)... Alcohol and alcoholism (Oxford, Oxfor... 2006
No negative associations were obtained for Fenugreek with Chemical and Drug Induced Liver Injury.


Linked Phytochemicals
PubChem ID Common Name Explore
5280343 Quercetin
5280805 Rutin
5281654 Isorhamnetin
689043 Caffeic Acid
667495 (2r)-Naringenin
Hyperglycemia 5, 0
Associations of Fenugreek with Hyperglycemia
PMID Disease Title Journal Year
28566642 Hyperglycemia Modulatory Effect of an Isolated Trig... Journal of oleo science 2017
26778682 Hyperglycemia Alterations in Plasma Glucose and Car... Canadian journal of diabetes 2016
24615531 Hyperglycemia Fenugreek potent activity against nit... Cytotechnology 2015
20540147 Hyperglycemia Diosgenin present in fenugreek improv... Molecular nutrition & food research 2010
20582202 Hyperglycemia Activity of Superoxide Dismutase and ... Indian journal of pharmaceutical scie... 2010
No negative associations were obtained for Fenugreek with Hyperglycemia.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Hyperglycemia association.
Metabolic Diseases 4, 0
Associations of Fenugreek with Metabolic Diseases
PMID Disease Title Journal Year
28599386 Metabolic Diseases Amelioration of hyperglycemia and ass... Journal of basic and clinical physiol... 2017
26732240 Metabolic Diseases Efficacy of Trigonella foenum-graecum... Iranian Red Crescent medical journal 2015
22113420 Metabolic Diseases Fenugreek improves diet-induced metab... Hormone and metabolic research = Horm... 2011
16477270 Metabolic Diseases Alleviation of hepatic steatosis acco... International journal of obesity (2005) 2006
No negative associations were obtained for Fenugreek with Metabolic Diseases.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Metabolic Diseases association.
Carcinogenesis 4, 0
Associations of Fenugreek with Carcinogenesis
PMID Disease Title Journal Year
20641053 Carcinogenesis The effect of fenugreek on the gene e... Phytotherapy research : PTR 2011
21629786 Carcinogenesis Diosgenin, a steroidal saponin, inhib... PloS one 2011
15298963 Carcinogenesis Diosgenin, a steroid saponin of Trigo... Cancer epidemiology, biomarkers & pre... 2004
14595593 Carcinogenesis Fenugreek affects the activity of bet... Phytotherapy research : PTR 2003
No negative associations were obtained for Fenugreek with Carcinogenesis.


Linked Phytochemicals
PubChem ID Common Name Explore
5280445 Luteolin
5280343 Quercetin
5280863 Kaempferol
5281855 Ellagic Acid
Kidney Diseases 3, 0
Associations of Fenugreek with Kidney Diseases
PMID Disease Title Journal Year
27151154 Kidney Diseases 4-Hydroxyisoleucine: A Potential New ... BioDrugs : clinical immunotherapeutic... 2016
25057273 Kidney Diseases Fenugreek Prevents the Development of... Evidence-based complementary and alte... 2014
20100065 Kidney Diseases Immunomodulatory, beta-cell, and neur... Immunopharmacology and immunotoxicology 2010
No negative associations were obtained for Fenugreek with Kidney Diseases.


Linked Phytochemicals
PubChem ID Common Name Explore
5280378 Formononetin
5280343 Quercetin
5280805 Rutin
5280445 Luteolin
5281855 Ellagic Acid
370 Gallic Acid
667495 (2r)-Naringenin
Gastrointestinal Diseases 3, 0
Associations of Fenugreek with Gastrointestinal Diseases
PMID Disease Title Journal Year
24289578 Gastrointestinal Diseases Fenugreek induced apoptosis in breast... Asian Pacific journal of cancer preve... 2013
22471470 Gastrointestinal Diseases Fenugreek, a naturally occurring edib... Asian Pacific journal of cancer preve... 2011
15298963 Gastrointestinal Diseases Diosgenin, a steroid saponin of Trigo... Cancer epidemiology, biomarkers & pre... 2004
No negative associations were obtained for Fenugreek with Gastrointestinal Diseases.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Gastrointestinal Diseases association.
Glucose Intolerance 3, 0
Associations of Fenugreek with Glucose Intolerance
PMID Disease Title Journal Year
26436069 Glucose Intolerance Role of Fenugreek in the prevention o... Journal of diabetes and metabolic dis... 2015
20100065 Glucose Intolerance Immunomodulatory, beta-cell, and neur... Immunopharmacology and immunotoxicology 2010
16718375 Glucose Intolerance Long-term effect of Trigonella foenum... Molecular and cellular biochemistry 2006
No negative associations were obtained for Fenugreek with Glucose Intolerance.


Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Fenugreek-Glucose Intolerance association.
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Phytochemicals in Fenugreek


PubChem ID Common Name Explore
6274 L-Histidine
23915 Schizandrin
99516 Tigogenin
370 Gallic Acid
667495 (2r)-Naringenin
5281675 Orientin
5280441 Vitexin
5281702 Tricin
5280460 Scopoletin
5282073 7,4'-Dihydroxyflavone
5280863 Kaempferol
5280445 Luteolin
5280805 Rutin
441899 Asparasaponin I
5281654 Isorhamnetin
689043 Caffeic Acid
5281855 Ellagic Acid
5280343 Quercetin
5570 Trigonelline
114776 Isoorientin
441900 Yamogenin
5280378 Formononetin
72 3,4-Dihydroxybenzoic Acid
5322065 7,3',4'-Trihydroxyflavone
6042 59-43-8