NCBI Taxonomy ID: 555479
Common Names: Black Caraway, Black Cumin, Caraway Seed
Scientific Name: Nigella Sativa
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Diseases associated with Black Cumin

Diseases Association Details
Diabetes Mellitus 30, 0
Associations of Black Cumin with Diabetes Mellitus
PMID Disease Title Journal Year
22477645 Diabetes Mellitus Mitigation of obesity-promoted diseas... Plant foods for human nutrition (Dord... 2012
24511321 Diabetes Mellitus Nigella sativa Fixed and Essential Oi... Evidence-based complementary and alte... 2014
26786775 Diabetes Mellitus Thymoquinone, a bioactive component o... American journal of physiology. Endoc... 2016
15482373 Diabetes Mellitus Nigella sativa seed extracts enhance ... Fundamental & clinical pharmacology 2004
19418593 Diabetes Mellitus Emerging clinical and therapeutic app... World journal of gastroenterology 2009
27279704 Diabetes Mellitus Minimization of the Risk of Diabetic ... Pharmacognosy magazine 2016
23674855 Diabetes Mellitus Effects of Nigella sativa on outcome ... World journal of gastroenterology 2013
28298934 Diabetes Mellitus The Antidiabetic Activity of <i>Nigel... Evidence-based complementary and alte... 2017
26445713 Diabetes Mellitus The effects of hydroalcoholic extract... Avicenna journal of phytomedicine 2015
16999030 Diabetes Mellitus Biochemical effects of Nigella sativa... Indian journal of experimental biology 2006
17052873 Diabetes Mellitus Ethnopharmacological survey of plants... Journal of ethnopharmacology 2007
20923501 Diabetes Mellitus Effects of Nigella sativa and thymoqu... Journal of diabetes 2010
27852303 Diabetes Mellitus The effects of Nigella sativa on thyr... BMC complementary and alternative med... 2016
19061948 Diabetes Mellitus Nigella sativa inhibits intestinal gl... Journal of ethnopharmacology 2009
24939518 Diabetes Mellitus Effect of Nigella sativa fixed and es... BMC complementary and alternative med... 2014
17395251 Diabetes Mellitus Combination therapy of Nigella sativa... Acta histochemica 2007
23267290 Diabetes Mellitus Hypoglycemic effect of lipoic Acid, c... International journal of health sciences 2011
27247923 Diabetes Mellitus Nigella sativa seed decreases endothe... Avicenna journal of phytomedicine 2016
11848252 Diabetes Mellitus Effect of Nigella sativa on glucose c... Journal of veterinary medicine. A, Ph... 2001
23429494 Diabetes Mellitus Nigella sativa and thymoquinone suppr... Pancreas 2013
27383323 Diabetes Mellitus Nigella sativa oil and thymoquinone a... European review for medical and pharm... 2016
23606883 Diabetes Mellitus In Vitro Evaluations of Cytotoxicity ... Evidence-based complementary and alte... 2013
21675032 Diabetes Mellitus Effect of Nigella sativa seeds on the... Indian journal of physiology and phar... 2010
25706772 Diabetes Mellitus Nigella sativa improves glycemic cont... PloS one 2015
19902033 Diabetes Mellitus Effect of Nigella sativa oil on vario... International journal of diabetes in ... 2008
25847566 Diabetes Mellitus Effects of black seed (Nigella sativa... Complementary therapies in medicine 2015
25859296 Diabetes Mellitus Black cumin (Nigella sativa) and its ... Iranian journal of basic medical scie... 2014
25859300 Diabetes Mellitus Cardio-protective and anti-cancer the... Iranian journal of basic medical scie... 2014
12443686 Diabetes Mellitus Isulinotropic properties of Nigella s... Research in veterinary science 2002
25983604 Diabetes Mellitus Nigella sativa: A potential natural p... Journal of family & community medicine 2015
No negative associations were obtained for Black cumin with Diabetes Mellitus.



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Diabetes Mellitus association.
Asthma 17, 0
Associations of Black Cumin with Asthma
PMID Disease Title Journal Year
22800928 Asthma Oral Nigella sativa oil ameliorates o... International immunopharmacology 2012
28093815 Asthma Nigella sativa Supplementation Improv... Phytotherapy research : PTR 2017
11381824 Asthma Bronchodilator, spasmolytic and calci... JPMA. The Journal of the Pakistan Med... 2001
15648658 Asthma Inhibition of 5-lipoxygenase and leuk... Journal of enzyme inhibition and medi... 2004
23754352 Asthma The main relaxant constituents of Nig... Iranian journal of allergy, asthma, a... 2013
16076084 Asthma An investigation on LD50 and subacute... Die Pharmazie 2005
16714217 Asthma Anti-inflammatory effect of thymoquin... International immunopharmacology 2006
16734144 Asthma Effect of dexamethasone and Nigella s... The Egyptian journal of immunology 2005
28187265 Asthma Gastroprotective effects of monteluka... Canadian journal of physiology and ph... 2017
25050269 Asthma Effect of Nigella sativa on the kidne... Avicenna journal of phytomedicine 2013
25150073 Asthma Effect of dexamethasone and Nigella s... Iranian journal of allergy, asthma, a... 2014
25752254 Asthma The protective effect of α-hederin, t... The journal of physiological sciences... 2015
25859296 Asthma Black cumin (Nigella sativa) and its ... Iranian journal of basic medical scie... 2014
16398273 Asthma Effects of aqueous and macerated extr... Die Pharmazie 2005
12722128 Asthma Pharmacological and toxicological pro... Phytotherapy research : PTR 2003
24298378 Asthma The Relaxant Effects of Different Met... Iranian journal of basic medical scie... 2013
26298318 Asthma Anti-inflammatory effects of thymoqui... Journal of neuroimmunology 2015
No negative associations were obtained for Black cumin with Asthma.



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Asthma association.
Inflammation 14, 0
Associations of Black Cumin with Inflammation
PMID Disease Title Journal Year
22590837 Inflammation Influence of Nigella sativa fixed oil... Pakistan journal of biological scienc... 2011
19913082 Inflammation Antimutagenic effects of ethanolic ex... Journal of ethnopharmacology 2010
22467430 Inflammation Characterization of thymoquinone bind... Journal of pharmaceutical sciences 2012
16714217 Inflammation Anti-inflammatory effect of thymoquin... International immunopharmacology 2006
24474661 Inflammation Anti-inflammatuar and anti-oxidative ... Molecular biology reports 2014
16734144 Inflammation Effect of dexamethasone and Nigella s... The Egyptian journal of immunology 2005
26956915 Inflammation Paracetamol-induced nephrotoxicity an... Pharmaceutical biology 2016
19010375 Inflammation In vitro toxicological properties of ... Food and chemical toxicology : an int... 2009
26826824 Inflammation Effect of lipid extracts of Nigella s... Pakistan journal of pharmaceutical sc... 2016
17324542 Inflammation Effects of aqueous extracts of medici... Journal of ethnopharmacology 2007
27247920 Inflammation Effects of Nigella sativa oil extract... Avicenna journal of phytomedicine 2016
23429494 Inflammation Nigella sativa and thymoquinone suppr... Pancreas 2013
22360025 Inflammation Effects of Nigella sativa and albenda... JPMA. The Journal of the Pakistan Med... 2011
26261504 Inflammation Nigella sativa amliorates inflammatio... International journal of clinical and... 2015
No negative associations were obtained for Black cumin with Inflammation.



Linked Phytochemicals
PubChem ID Common Name Explore
5280934 Linolenic Acid
10281 Thymoquinone
10364 Carvacrol
Carcinogenesis 12, 0
Associations of Black Cumin with Carcinogenesis
PMID Disease Title Journal Year
18570215 Carcinogenesis Role of Nigella sativa and a number o... Phytotherapy research : PTR 2008
16684351 Carcinogenesis A long-term investigation of the anti... Journal of carcinogenesis 2006
28324259 Carcinogenesis Protective effect of Nigella sativa s... Environmental science and pollution r... 2017
19418593 Carcinogenesis Emerging clinical and therapeutic app... World journal of gastroenterology 2009
12881014 Carcinogenesis Chemopreventive potential of volatile... Nutrition and cancer 2003
1923908 Carcinogenesis Inhibitory effects of Nigella sativa ... Nutrition and cancer 1991
23317266 Carcinogenesis Antiproliferative properties of metha... Asian Pacific journal of cancer preve... 2012
15785320 Carcinogenesis Inhibition of two stage renal carcino... European journal of cancer prevention... 2005
15916774 Carcinogenesis Cytotoxic effects of a decoction of N... Life sciences 2005
27649635 Carcinogenesis Recent advances on the anti-cancer pr... Journal of Ayurveda and integrative m... 2016
12385575 Carcinogenesis Inhibition of methylnitrosourea (MNU)... Journal of experimental & clinical ca... 2002
14613573 Carcinogenesis Protection against diethylnitrosoamin... Journal of carcinogenesis 2003
No negative associations were obtained for Black cumin with Carcinogenesis.



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Carcinogenesis association.
Neoplasms 11, 0
Associations of Black Cumin with Neoplasms
PMID Disease Title Journal Year
28693287 Neoplasms Effect of thymoquinone on head and ne... Oncology letters 2017
28694778 Neoplasms North African Medicinal Plants Tradit... Frontiers in pharmacology 2017
16684351 Neoplasms A long-term investigation of the anti... Journal of carcinogenesis 2006
22477645 Neoplasms Mitigation of obesity-promoted diseas... Plant foods for human nutrition (Dord... 2012
27529277 Neoplasms Spices for Prevention and Treatment o... Nutrients 2016
20712304 Neoplasms Total synthesis and anticancer activi... The Journal of organic chemistry 2010
24959190 Neoplasms Therapeutic Implications of Black See... Evidence-based complementary and alte... 2014
22966405 Neoplasms Cancer chemopreventive potential of v... Oncology letters 2010
25241984 Neoplasms Apoptotic activities of thymoquinone,... The Chinese journal of physiology 2014
24044882 Neoplasms Molecular targeting of Akt by thymoqu... Life sciences 2013
20423995 Neoplasms Effects of thymoquinone in the expres... Molecular cancer therapeutics 2010
No negative associations were obtained for Black cumin with Neoplasms.



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Neoplasms association.
Chemical and Drug Induced Liver Injury 9, 1
Associations of Black Cumin with Chemical and Drug Induced Liver Injury
PMID Disease Title Journal Year
22539463 Chemical and Drug Induced Liver Injury Cadmium-induced hepatotoxicity and it... Journal of biochemical and molecular ... 2012
15154284 Chemical and Drug Induced Liver Injury The effect of Nigella sativa oil on g... The American journal of Chinese medicine 2004
26826824 Chemical and Drug Induced Liver Injury Effect of lipid extracts of Nigella s... Pakistan journal of pharmaceutical sc... 2016
25053547 Chemical and Drug Induced Liver Injury Protective effect of Nigella sativa o... Chinese journal of natural medicines 2014
27814700 Chemical and Drug Induced Liver Injury The hepatoprotective activity of oliv... BMC complementary and alternative med... 2016
11848252 Chemical and Drug Induced Liver Injury Effect of Nigella sativa on glucose c... Journal of veterinary medicine. A, Ph... 2001
25675711 Chemical and Drug Induced Liver Injury Therapeutic efficacy of Nigella sativ... Indian journal of experimental biology 2015
25809628 Chemical and Drug Induced Liver Injury Therapeutic value of black seed oil i... Infectious disorders drug targets 2015
14696675 Chemical and Drug Induced Liver Injury Protective effect of Nigella sativa s... The American journal of Chinese medicine 2003
16076084 Chemical and Drug Induced Liver Injury An investigation on LD50 and subacute... Die Pharmazie 2005



Linked Phytochemicals
PubChem ID Common Name Explore
5280934 Linolenic Acid
10281 Thymoquinone
101977 D-Citronellol
Kidney Diseases 7, 1
Associations of Black Cumin with Kidney Diseases
PMID Disease Title Journal Year
28629150 Kidney Diseases Role of Nigella sativa and Its Consti... Nutrients 2017
26352334 Kidney Diseases Study on the effect of black cumin (N... Acta cirurgica brasileira 2015
15154284 Kidney Diseases The effect of Nigella sativa oil on g... The American journal of Chinese medicine 2004
23009987 Kidney Diseases Nephro-protective effect of vitamin C... Pakistan journal of pharmaceutical sc... 2012
9609969 Kidney Diseases Protective effect of cysteine and vit... Journal de pharmacie de Belgique 1998
27247917 Kidney Diseases Renal injury, nephrolithiasis and Nig... Avicenna journal of phytomedicine 2016
27247921 Kidney Diseases The protective effect of Nigella sati... Avicenna journal of phytomedicine 2016
18223305 Kidney Diseases Nigella sativa oil for prevention of ... American journal of nephrology 2008



Linked Phytochemicals
PubChem ID Common Name Explore
4276 Myristicin
10281 Thymoquinone
Arthritis 7, 0
Associations of Black Cumin with Arthritis
PMID Disease Title Journal Year
19913082 Arthritis Antimutagenic effects of ethanolic ex... Journal of ethnopharmacology 2010
22467430 Arthritis Characterization of thymoquinone bind... Journal of pharmaceutical sciences 2012
19010375 Arthritis In vitro toxicological properties of ... Food and chemical toxicology : an int... 2009
26826824 Arthritis Effect of lipid extracts of Nigella s... Pakistan journal of pharmaceutical sc... 2016
21127340 Arthritis Thymoquinone inhibits matrix metallop... Experimental biology and medicine (Ma... 2010
17324542 Arthritis Effects of aqueous extracts of medici... Journal of ethnopharmacology 2007
26298318 Arthritis Anti-inflammatory effects of thymoqui... Journal of neuroimmunology 2015
No negative associations were obtained for Black cumin with Arthritis.



Linked Phytochemicals
PubChem ID Common Name Explore
10281 Thymoquinone
Liver Failure 6, 0
Associations of Black Cumin with Liver Failure
PMID Disease Title Journal Year
19913082 Liver Failure Antimutagenic effects of ethanolic ex... Journal of ethnopharmacology 2010
22467430 Liver Failure Characterization of thymoquinone bind... Journal of pharmaceutical sciences 2012
19010375 Liver Failure In vitro toxicological properties of ... Food and chemical toxicology : an int... 2009
26826824 Liver Failure Effect of lipid extracts of Nigella s... Pakistan journal of pharmaceutical sc... 2016
17324542 Liver Failure Effects of aqueous extracts of medici... Journal of ethnopharmacology 2007
22186327 Liver Failure Supplementation of Nigella sativa fix... Pakistan journal of pharmaceutical sc... 2012
No negative associations were obtained for Black cumin with Liver Failure.



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Liver Failure association.
Diarrhea 4, 1
Associations of Black Cumin with Diarrhea
PMID Disease Title Journal Year
11381824 Diarrhea Bronchodilator, spasmolytic and calci... JPMA. The Journal of the Pakistan Med... 2001
16076084 Diarrhea An investigation on LD50 and subacute... Die Pharmazie 2005
22768141 Diarrhea Nigella sativa (black cumin) seed ext... PloS one 2012
12722128 Diarrhea Pharmacological and toxicological pro... Phytotherapy research : PTR 2003
24311845 Diarrhea Nigella sativa concoction induced sus... African journal of traditional, compl... 2013



Linked Phytochemicals
PubChem ID Common Name Explore
No linked phytochemicals found for Black cumin-Diarrhea association.
Page 1 of 12



Phytochemicals in Black Cumin


PubChem ID Common Name Explore
17868 Alpha-Thujene
10281 Thymoquinone
4276 Myristicin
7460 Alpha-Phellandrene
6654 Alpha-Pinene
7439 Carvone
101977 D-Citronellol
7463 P-Cymene
8815 Estragole
31253 Myrcene
14896 Beta-Pinene
8141 Nonane
7462 Alpha-Terpinene
31244 4-Methoxybenzaldehyde
14525 Fenchone
3893 Lauric Acid
11230 Terpinen-4-Ol
18818 Sabinene
289151 Longifolene
10364 Carvacrol
520957 .Alpha.-Longipinene
10659 Apiole
24473 Dihydrocarvone
6989 Thymol
5280934 Linolenic Acid
445639 Oleic Acid